The virus was most pathogenic to the newborn mice, causing death in many of them. americanum nymph, it was inoculated into many test animals including: newborn and full-grown mice, woodchucks, raccoons, as well as chicken and duck eggs. Research Īfter the virus was isolated from the A. This means this disease could likely be something that affects humans in the future, or has had an effect, but has not been documented, or traced back to this source. No human cases have been found thus far, however evidence points to the fact that it does have pathogenic effects in humans. As part of the minimal research that has been done, death occurred in mice that were infected with the virus. The virus is shown to have a cytopathic effect on both human ( HeLa) and monkey ( vero) cells. This increase in number will cause more humans to come in contact with lone star ticks, and could possible lead to a human being affected by the virus. This tick used to exist mainly in the South-Central United States, however it has increased in both range and abundance over the past twenty years, to now exist along most of the Southern states and the Eastern Coast of the United States. It is found to be present in the Lone star tick. There has not been any documented case of Lone star virus causing illness in a human. The viruses size is between 90 and 100 micrometers. Finding a link between the two will help them to understand both of these viruses on a greater level. They are also curious as to whether LSV virus could be found in patients who have STARI. It is the hope of the scientific community that researching Lone star virus can give clues to the etiology of STARI.
Interest has recently increased in it due to the emergence of STARI, or Southern Tick-borne Rash Illness, an unknown disease which is also associated with Amblyomma americanum. Although it was discovered in 1967, it has never been genetically characterized. It has been proven to produce titers in human and monkey cells seventy-two hours after inoculation. Its genus is Bandavirus and its species name is Lone star bandavirus. It is in the Bunyaviridae family of viruses. Lone star virus's genome consist of negative, single-stranded RNA.
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